TRIFLUOROACETIC ACID (TFA) is an important building block in the synthesis of pharmaceutical, agrochemical and performance products. It is a reagent of choice in peptide synthesis, as Boc deprotecting agent, peptide cleavage and purification solvant. It is widely used as a solvant and as a catalyst for polymerization and condensation reactions. It is also used in the manufacture of high performance coatings.


  • CAS number
  • Global Business Unit
    Special Chem
  • Synonyms


Segments Applications
Crop Protection Active | Solvent
Segments Applications
Pharmaceuticals Active | Intermediates

Chemical categories

Chemical category Chemical family Chemical product
Fluorine derivatives Fluorinated Chemicals Trifluoroacetic acid

Region of commercial availability

  • Asia / Pacific
  • Europe / Middle East / Africa
  • North America
  • Latin America

Download documentation for TRIFLUOROACETIC ACID (TFA)