Raw materials, Intermediates & Active ingredients
The use of organic fluorinated intermediates has become indispensable in the development of breakthrough innovations across the agrochemical and pharmaceutical industries.
Approximately 30% of drugs and 50% of crop protection products under development contain fluorine, highlighting the critical role of these compounds.
Explore Our Fluorinated Product Portfolio
Leveraging our long-standing expertise in fluorine chemistry, we deliver high-quality products tailored through efficient and advanced production processes, ensuring optimal performance and reliability for your applications.
Fluorinated Esters and Acetoacetates
ETFBO is a new synthetic building block containing fluorine.
Compounds containing such building blocks reach cells easier and are therefore more effective. Thus, less application is required to achieve the same effect.
ETFBO not only allows lower dosages, but generates a predetermined breaking point in the molecule at which, for example, soil organisms attack. The fluorine thereby ensures that the molecule decomposes on the field and does not affect the environment.
Features & benefits
- Approximately 30% of newly developed drugs and approximately 50% of crop protection products contain fluorine
- Because of higher lipophilicity, compounds with fluorine components have better absorption in animal and plant cells (better migration through cell membranes)
- It enables lower doses in drugs and medicines and is more tolerable
- It carries favorable properties into molecules, such as activity and metabolic stability
- Environmental friendly as fluorine with a strong –I effect, it can generate a breaking point in the active ingredient
Solvay offers extensive expertise in the development and manufacturing of fluorinated compounds, including Trifluoroacetic Acid (TFA) and its derivatives. With a focus on creating efficient and cost-effective production processes, Solvay supports the synthesis of innovative molecules used in pharmaceuticals, agrochemicals, and other industries. Starting with the development of new molecules based on TFAC and first sample preparation through to the full set of necessary HSE and REACH registration, we are your partner.
Key Applications of TFA and Derivatives
TFA plays a critical role across various sectors:
Agrochemicals
Fluorine's unique biological properties make it a key component in agrochemical development, with approximately 50% of fluorinated intermediates in progress within the industry. Solvay focuses on developing cost-competitive, sustainable, and safe production processes for existing and novel fluorinated molecules. Manufacturing adheres to strict Health, Safety, and Environmental (HSE) standards, leveraging in-house production and an extensive toller network.
Pharmaceuticals
Solvay provides the pharmaceutical sector with a diverse range of fluorinated raw materials derived from its CF2/CF3 product tree. Fluorine is a critical element in many blockbuster drugs, including those targeting pain relief (analgesics), infections (antibiotics, antivirals), and chronic conditions (anticancer agents, anti-HIV drugs).
Industrial Applications
Fluorinated compounds serve versatile roles in industrial settings:
- Electronic and Coating Additives: Used in electronic conducting materials and coatings for advanced technologies like flat panel displays and fingerprint scanners.
- Solvents and Catalysts: Fluorinated acids, alcohols, and ketones are valued for their excellent solvent properties, facilitating chemical reactions and acting as catalysts for processes like silicone and alkylation reactions.
Explore TFA derivatives
Trifluoroacetyl chloride - Fluorinated Acid Chlorides
Trifluoroacetic acid anhydride - Fluorinated Anhydrides
Trifluoroacetic acid ethyl ester - Fluorinated Esters and Acetoacetates
Trifluoroacetic acid isopropyl ester - Fluorinated Esters and Acetoacetates
Trifluoroacetic acid methyl ester - Fluorinated Esters and Acetoacetates
1,1,1-Trifluoroacetone - Fluorinated Ketones
Explore all products for Organic Fluorinated Compounds
